Player of the Year: Trustin Baker, Nixa
Offensive Player of the Year: Joey Clem, Nixa
Defensive Player of the Year: Jonathan Dasal, Nixa
Goalkeeper of the Year: Jakob Price, Nixa
Coach of the Year: Evan Palmer, Nixa
| Full Class 4 All-Region Team | |||
| Player | School | Year | Position |
| Jonathan Dasal | Nixa | JR | D |
| Bailey Williams | Ozark | SR | D |
| Serafin Gonzalez | Ozark | SR | D |
| Joey Clem | Nixa | SR | F |
| Parker Crawford | Nixa | JR | F |
| Josh Ellerbee | Kickapoo | SR | F |
| Pavin Winkle | Joplin | JR | F |
| Caleb Rodriguez | Waynesville | SR | F |
| Jaime Villegas | Central | JR | F |
| Brody Johnson | Parkview | JR | F |
| Jakob Price | Nixa | SO | GK |
| Trustin Baker | Nixa | SR | MF |
| Sam Hockett | Kickapoo | SR | MF |
| Manny Torres | Central | SR | MF |